Background: The angiotensin receptor neprilysin inhibitor sacubitril-valsartan is included in the first-line treatment for patients with heart failure (HF) and left ventricle ejection fraction (LVEF). Three clinical trials have evaluated the effect of sacubitril-valsartan in 3 different clinical...

Inefficiency in the U.S. health care system has often been characterized as "flat of the curve" spending providing little or no incremental value. In this paper, we draw on macroeconomic models of diffusion and productivity to better explain the empirical patterns of outcome improvements in...

During the past two decades, several public and private organizations have initiated programs to report publicly on the quality of medical care provided by specific hospitals and physicians. These programs have sparked broad debate among economists and policy makers concerning whether, and to...