Proteins are important molecules that are widely studied in biology. Since their three-dimensional conformations can give clues about their function, an optimal methodology for the identification of such conformations has been researched for many years. Experiments of Nuclear Magnetic Resonance...

The Distance Geometry Problem in three dimensions consists in finding an embedding in <InlineEquation ID="IEq1"> <EquationSource Format="TEX">$${\mathbb{R}^3}$$</EquationSource> </InlineEquation> of a given nonnegatively weighted simple undirected graph such that edge weights are equal to the corresponding Euclidean distances in the embedding. This is a continuous search problem...</equationsource></inlineequation>

This paper discusses the use of probabilistic or randomized algorithms for solving vehicle routing problems with non-smooth objective functions. Our approach employs non-uniform probability distributions to add a biased random behavior to the well-known savings heuristic. By doing so, a large...

The table placement problem consists in deciding how to seat the participants attending a social lunch or dinner so that the total social benefit of the event is maximum. Four different approaches are presented: a linear model, a bin-packing-based-approach, a quadratic assignment problem, and a...

In this paper, we propose a new integer linear programming (ILP) formulation for solving a file transfer scheduling problem (FTSP), which is to minimize the overall time needed to transfer all files to their destinations for a given collection of various sized files in a computer network. Each...

The single-row facility layout problem <Emphasis FontCategory="NonProportional">(SRFLP) is an NP-hard combinatorial optimization problem that is concerned with the arrangement of n departments of given lengths on a line so as to minimize the weighted sum of the distances between department pairs. <Emphasis FontCategory="NonProportional">(SRFLP) is the one-dimensional version...</emphasis></emphasis>

In this note, we prove ??-completeness of the following problem: Given a set of trams of different types, which are stacked on sidings in their depot and an order in which trams of specified types are supposed to leave. Is there an assignment of trams to departure times without any shunting...

In the generalized balanced optimization problem (GBaOP) the objective value <InlineEquation ID="IEq1"> <EquationSource Format="TEX">$${\max_{e \in S}{|c(e)-k\max(S)|}}$$</EquationSource> </InlineEquation> is minimized over all feasible subsets S of E = {1, . . . , m}. We show that the algorithm proposed in Punnen and Aneja (Oper Res Lett 32:27–30, <CitationRef CitationID="CR14">2004</CitationRef>) can be modified to...</citationref></equationsource></inlineequation>

The floorplanning (or facility layout) problem consists in finding the optimal positions for a given set of modules of fixed area (but perhaps varying height and width) within a facility such that the distances between pairs of modules that have a positive connection cost are minimized. This is...

Traditional auction mechanisms support price negotiations on a single item. The Internet allows for the exchange of much more complex offers in real-time. This is one of the reasons for much research on multidimensional auction mechanisms allowing negotiations on multiple items, multiple units,...