Objective: The objective of this paper is to examine how well the QALY captures the health gains generated by cancer treatments, with particular focus on the methods for constructing QALYs preferred by NICE. Methods: Data were obtained using a keyword search of the MEDLINE database and a hand...

Objectives: This research was intended to explore whether wealth effects of drug interventions, including productivity gains and savings in other sectors, are considered in resource allocations by health technology assessment (HTA) agencies and government departments. It also analyses reasons...

Knowing the net value that companies, or whole sectors of the economy, bring is clearly important when considering economic and industrial policy. In this paper we estimate the economic contribution to the UK made by two British based, research intensive, pharmaceutical companies: AstraZeneca...

Objectives: The purpose of this research is to identify the attributes to include in an orphan medicinal product (OMP) value framework, determine their relative importance via a multi-criteria decision analysis (MCDA) process, and test whether an MCDA approach can practically support decision...

Background: It is often assumed that the objective of health care is to maximise health using available resources. This is the principle underpinning NICE's use of cost effectiveness analysis based on incremental cost per QALY gained. Yet research on local NHS decision making shows that cost per...

We examine corporate publishing - i.e. firms' involvement in the production of scientific publications - with two research questions. First, why do firms publish? Through systematic literature review, we propose a framework of five incentives for firms to publish: (i) accessing external...

We examine corporate publishing - i.e. firms' involvement in the production of scientific publications - with two research questions. First, why do firms publish? Through systematic literature review, we propose a framework of five incentives for firms to publish: (i) accessing external...

We examine corporate publishing-i.e. firms' involvement in the production of scientific publications-with two research questions. First, why do firms publish? Through systematic literature review, we propose a framework of five incentives for firms to publish: (i) accessing external knowledge...

The budget battles of recent years have amplified the warnings of demographic doomsayers who predicted that a wave of baby boomers would bleed America dry, bankrupting Social Security and Medicare as they faded into an impoverished old age. On the contrary, argues award-winning journalist Chris...