We develop an algorithm that incorporates network information into regression settings. It simultaneously estimates the covariate coefficients and the signs of the network connections (i.e. whether the connections are of an activating or of a repressing type). For the coefficient estimation...

We develop an algorithm that incorporates network information into regression settings. It simultaneously estimates the covariate coefficients and the signs of the network connections (i.e. whether the connections are of an activating or of a repressing type). For the coefficient estimation...

Often, variables are linked to each other via a network. When such a network structure is known, this knowledge can be incorporated into regularized regression settings via a network penalty term. However, when the type of interaction via the network is unknown (that is, whether connections are...

Often, variables are linked to each other via a network. When such a network structure is known, this knowledge can be incorporated into regularized regression settings via a network penalty term. However, when the type of interaction via the network is unknown (that is, whether connections are...

Covariates in regressions may be linked to each other on a network. Knowledge of the network structure can be incorporated into regularized regression settings via a network penalty term. However, when it is unknown whether the connection signs in the network are positive (connected covariates...

We develop an algorithm that incorporates network information into regression settings. It simultaneously estimates the covariate coefficients and the signs of the network connections (i.e. whether the connections are of an activating or of a repressing type). For the coefficient estimation...

Current technologies generate a huge number of single nucleotide polymorphism (SNP) genotype measurements in case-control studies. The resulting multiple testing problem can be ameliorated by considering candidate gene regions. The <Emphasis Type="Bold">minPtest R package provides the first widely accessible...</emphasis>

The bootstrap is a tool that allows for efficient evaluation of prediction performance of statistical techniques without having to set aside data for validation. This is especially important for high-dimensional data, e.g., arising from microarrays, because there the number of observations is...