This paper presents a comprehensive socio-technical framework for the design and development of a Clinical and Translational Science Informatics Infrastructure (CTSII). Based on our experience with developing and applying the framework we present a case study to illustrate the issues that arise...

The objective of Clinical and Translational Science (CTS) is to reduce the time-to-practice of biomedical scientific discoveries, and the time-to-research of clinical and community health care issues. The guiding mission of the Biomedical Informatics Infrastructure (BII) is to provide the...

This paper presents an ontology of a cyberenvironment for malaria surveillance. The ontology encapsulates a comprehensive natural language enumeration of the requirements of the cyberenvironment using a structured terminology. It can be used to systematically analyze and prioritize the functions...