to consider a well known game of tumor metabolism and use our approach to derive potential new cancer treatment …

Cancer cells and stromal cells often exchange growth factors with paracrine effects that promote cell growth: a form of …

evolutionary game theory of cancer, but the approach can be used for a wide range of nonlinear public goods games. …

For cancer, we develop a 2-D agent-based continuous-space game-theoretical model that considers cancer cells’ proximity … to a blood vessel. Based on castrate resistant metastatic prostate cancer (mCRPC), the model considers the density and … frequency (eco-evolutionary) dynamics of three cancer cell types: those that require exogenous testosterone ( T + ), those …

Prostate cancer to bone metastases are almost always lethal. This results from the ability of metastatic prostate … cancer cells to co-opt bone remodeling, leading to what is known as the vicious cycle. Understanding how tumor cells can … model of both the homeostatic bone remodeling and its co-option by prostate cancer metastases. This model extends past the …

The likelihood of cancer emergence is highly dependent on the underlying tissue structure. This article gives … cancer. In a second step, a mathematical framework is proposed, within which the risk of cancer emergence can be expressed …