Maintaining a rich research and development (R&D) pipeline is the key to remaining competitive in many industrial sectors. Due to its nature, R&D activities are subject to multiple sources of uncertainty, the modeling of which is compounded by the ability of the decision maker to alter the...

A previous study on Sunshine to Petrol (S2P), a technology framework to produce liquid hydrocarbon fuels from CO2 and water using a concentrated solar energy source, focused on process development as well as economic evaluation. The study herein presents results from a life cycle assessment...

We discuss methods for the solution of a multi-stage stochastic programming formulation for the resource-constrained scheduling of clinical trials in the pharmaceutical research and development pipeline. First, we present a number of theoretical properties to reduce the size and improve the...