An estimand of interest in empirical studies with observational data is the average treatment effect of a multi-valued treatment in the treated subpopulation. We demonstrate three estimation approaches: outcome regression, inverse probability weighting and inverse probability weighted...

An estimand of interest in empirical studies with observational data is the average treatment effect of a multi-valued treatment in the treated subpopulation. We demonstrate three estimation approaches: outcome regression, inverse probability weighting and inverse probability weighted...

Abstract The between-within (BW) model is a popular regression model for twin data. Despite its popularity, the properties of the BW model have not yet been thoroughly investigated, and most reviews are largely heuristic. The aim of this paper is to provide a formal guide to the causal...

Abstract The attributable fraction is a common measure in epidemiological research, which quantifies the public health impact of a particular exposure on a particular outcome. Often, the exposure effect may be mediated through a third variable, which lies on the causal pathway between the...

Abstract Unmeasured confounding is one of the most important threats to the validity of observational studies. In this paper we scrutinize a recently proposed sensitivity analysis for unmeasured confounding. The analysis requires specification of two parameters, loosely defined as the maximal...

Abstract Unmeasured confounding is an important threat to the validity of observational studies. A common way to deal with unmeasured confounding is to compute bounds for the causal effect of interest, that is, a range of values that is guaranteed to include the true effect, given the observed...

Abstract Biological and epidemiological phenomena are often measured with error or imperfectly captured in data. When the true state of this imperfect measure is a confounder of an outcome exposure relationship of interest, it was previously widely believed that adjustment for the mismeasured...

Abstract Residual confounding is a common source of bias in observational studies. In this article, we build upon a series of sensitivity analyses methods for residual confounding developed by Brumback et al. and Chiba whose sensitivity parameters are constructed to quantify deviation from...

Abstract It is well-known that dichotomization can cause bias and loss of efficiency in estimation. One can easily construct examples where adjusting for a dichotomized confounder causes bias in causal estimation. There are additional examples in the literature where adjusting for a dichotomized...

The goal of this review is to enable clinical psychology researchers to more rigorously test competing hypotheses when studying risk factors in observational studies. We argue that there is a critical need for researchers to leverage recent advances in epidemiology/biostatistics related to...