A hierarchical scheme for cooperativity and folding in proteins
We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first-order phase transition, cooperativity and is exactly solvable. It also shows an unexpected symmetry between folding and unfolding pathways as suggested by a recent experiment.
Year of publication: |
1998
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Authors: | Hansen, Alex ; Jensen, Mogens H. ; Sneppen, Kim ; Zocchi, Giovanni |
Published in: |
Physica A: Statistical Mechanics and its Applications. - Elsevier, ISSN 0378-4371. - Vol. 250.1998, 1, p. 355-361
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Publisher: |
Elsevier |
Saved in:
Online Resource
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