Role of Green Tea Extract and Powder To Mitigate Metabolic Syndromes; Special Reference To Hyperglycemia and Hypercholesterolemia
Currently dependence on natural products is gaining popularity to combat various physiological threats. Scientific evidences have been provided that dietary phytochemicals may play important roles as chemo-preventive or chemotherapeutic agents in the prevention of many diseases. Green tea has many biologically active moieties like flavanols and polyphenols. Catechins are flavanols that constitute majority of soluble solids of green tea; its major fractions are epigallocatechingallate (EGCG), epigallocatechin (EGC), epicatechingallate (ECG) and epicatechin (EC). Among these, EGCG is the predominant fraction contributing more than 50% of polyphenols. It has many health related characteristics like hypoglycemic, hypocholesterolemic, anticancer, antiviral and antihypertensive. Ethanolic extracts of green tea was subjected to in vivo modeling. Efficacy trial was carried out on normal, hyperglycemic and hypercholesterolemic rats for 8 weeks study. Control, functional and nutraceutical diets were used for each study. Drink & feed intake and body weight increased during the study period. Serum analysis depicted that maximum reduction of cholesterol level was noted in hypercholesterolemic rats up to 15.45 % due to nutraceutical diet. It was 21.51 % in case of LDL and 12.92 % for triglycerides. The serum glucose level was reduced maximum in hyperglycemic rats up to 13.39 % as a result of nutraceutical diet. The functional diet resulted in a bit less reduction in the respective traits as compared to nutraceutical diet. Hematological analysis revealed that administration of green tea did not adversely affect the red blood cell, white blood cells and platelets count of the rats. The current research work enables us to conclude that green tea is effective against hypercholesterolemia and hyperglycemia.
Year of publication: |
2013
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Authors: | Yousaf, S. ; Butt, M. S. ; Suleria, H. A. R. ; Iqbal, M. J. ; Sohail, M. |
Published in: |
International Proceedings of Social and Behavioral Sciences. - Pak Publishing Group. - Vol. 1.2013, 1, p. 105-122
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Publisher: |
Pak Publishing Group |
Saved in:
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