Truth, Disclosure and the Influence of Industry on the Development of NICE Guidelines: An Interview with Tim Kendall

The selective publication of clinical trials by the pharmaceutical industry and by academic investigators has long been a contentious area in medicine. Clinicians and scientists such as Iain Chalmers, one of the founders of the UK Cochrane Centre, have worked for over two decades to address the problem of the under-reporting of research, suggesting that the failure to report clinical trials breaks ‘an implicit contract with the patients who had participated in them’, and should in some cases be treated as scientific misconduct (Chalmers, 1990, 20