Methods: A decision tree model was built with life years gained as outcome, from the perspective of the health system, and including all direct costs. Pharmaceutical prices were obtained from the System of Information of Medicaments SISMED (2008), and the value of procedures was calculated from...

Objetive: To assess the cost effectiveness of unrelated stem cell transplantation versus consolidation chemotherapy in pediatric population with high-risk acute myeloid leukemia (AML).Methods: A decision tree model was built with life years gained as outcome, from the perspective of the health...

Markov-based and discrete event simulation models are widely used in health economic analysis to estimate the long term effects of treatment on clinical and economic outcomes. However, none of them simultaneously integrate patients' economic resources and their medical decision making in the...

Comparative effective research (CER) compares alternative methods of preventing, diagnosing, treating, and otherwise managing medical conditions. The Patient Protection and Affordable Care Act authorized creation and funding of an independent agency, the Patient-Centered Outcomes Research...