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Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Chapter 1 Introduction -- 1.1 Quality by Design Overview -- 1.2 Pharmaceutical Industry -- 1.3 Quality by Design Details -- 1.4 Chapter Summaries -- References -- Chapter 2 An Overview of the Role of Mathematical...
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The price of new brand-name prescription drugs has been rising fast in the US. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year. Patients, even with insurance coverage, must pay out-of-pocket a significant portion of this price. The treatment might...
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Erstattungsbetragsverhandlungen innovativer Arzneimittel werden als Gefahr für die zukünftige Versorgung der Patienten und für den Forschungs- und … zweckmäßigen Vergleichstherapie gleichwertige Arzneimittel schlechter gestellt werden. Zum anderen können nur noch … Arzneimittel beeinflusst darüber hinaus die Standortentscheidungen pharmazeutischer Unternehmen. …
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Almost two millennia ago, Archimedes explained that the shortest distance between two points is a straight line. That fundamental principle has been lost in the strange, meandering design of the nation’s pharmaceutical supply system. The result, as Archimedes would have predicted, is...
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