Aims: To develop a model for evaluating screening strategies and to use it to determine the cost effectiveness of varying the screening method and the screening interval.Methods: A discrete event simulation was designed, validated and run for a population of 500 000. Most parameters were derived...

Applied Game Theory has been criticised for not being able to model real decision making situations. A game's sensitive nature and the difficultly in determining the utility payoff functions make it hard for a decision maker to rely upon any game theoretic results. Therefore the models tend to...

A review of the basic theory of optimal open-source software contributions points to three key factors affecting the decision to contribute to the open-source development process: non-pecuniary benefits, future expected monetary returns, and open-source licence type. This paper argues that...

We have evaluated the power for detecting a common trait determined by two loci, using seven statistics, of which five are implemented in the computer program SimWalk2, and two are implemented in GENEHUNTER. Unlike most previous reports which involve evaluations of the power of allele-sharing...

We demonstrate an approach to low-dimensional modeling of world population, carbon dioxide (CO2) emissions and gross domestic product (GDP) interactions in a way that explicitly characterizes the variability in the data informing model assumptions and the uncertainty in functional relationships....

During recent years increasing interest has been shown in the theoretical calculation of three dimensional ship motions using singularity distribution methods and the coupled element method. Any practical calculation, particularly for a surface ship requires an efficient numerical scheme for...

Purpose: the paper reports from an exploratory study into how small businesses use Web 2.0 information and communication technologies (ICT) to work collaboratively with other small businesses. The study had two aims: to investigate the benefits available from the use of Web 2.0 in small business...

This paper focuses on the integrative and pervasive use of microcomputers in marketing research and managerial decision making. The marketing research process is conceptualized as consisting of six phases. At each phase, microcomputer applications and illustrative software are identified as...

Empirical research is vital if software engineering technology is to be meaningfully evaluated --- without it only guesses can be made at the competing merits of different approaches. Unfortunately, as this thesis demonstrates, much of existing empirical work contains some kind of weakness...

Many papers have speculated on the possibility of applying peer-to-peer networking concepts to networks that exist in the physical world such as financial markets, business or personal communication and ad hoc networking. One such application that has been discussed in the literature has been...